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viva-tumor-tcell
A multiscale agent-based tumor microenvironment model with tumor, T-cell, and dendritic-cell processes, diffusing IFNg and tumor-debris fields, cell-cell neighbor exchange, and phenotype conversion/exhaustion dynamics.
viva-tumor-Vivarium-2
A process-bigraph port of the multiscale agent-based tumor microenvironment model, including tumor, T-cell, and dendritic-cell biology, diffusing IFNg and tumor-debris fields, and cell-cell neighbor exchange.
Goldbeter1991 - Min Mit Oscil
A minimal model for the mitotic oscillator in early amphibian embryos, representing cyclin-driven activation of cdc2 kinase, cdc2-driven activation of cyclin protease, and delayed negative feedback through cyclin degradation.
Malinzi2018 - Enhancement of chemotherapy using oncolytic virotherapy
IA spatio-temporal mathematical model, in the form of a moving boundary problem, to explain cancer dormancy. Analysis covers temporal and spatio-temporal cases, stability, travelling waves, minimum invasion wave speeds, and numerical simulations of immune-induced tumour dormancy.
Nwabugwu2013 - A Tumor-Immune Mathematical Model of CD4+ T Helper Cell
Its a mathematical model presenting the interaction between a growing tumor and immune system. Model involves tumor cells, dendritic cell, helper Tcells, regulatory Tcells, effector cells and certain cytokines (e.g. TGFbeta, IL10, IL2 ) produced by these cells. It represent a dynamic regulation of tumor production/killing by different immune cells and cytokines. Model is derived from Tessi-Roberton 2012.
Tumor/T cell Microenvironment ABM
The model represents tumor cells, T cells, and related processes in a spatial microenvironment, including intracellular and intercellular interactions, soluble factors, cell movement, molecular fields, proliferation, phenotype changes, and cytotoxic killing. It is implemented on the Vivarium framework and can be initialized with multiplexed imaging datasets.
Covasim
Covasim performs projections of indicators such as numbers of infections and peak hospital demand, and explores interventions including social distancing, school closures, testing, contact tracing, quarantine, and vaccination.
viva-amici
A process-bigraph bridge that compiles Antimony or SBML models into AMICI per-model C++/SWIG extensions and integrates them with SUNDIALS CVODES, exposing time-stepped and one-shot simulation processes plus exponential-decay, Lotka-Volterra, and MAPK cascade composites.
viva-simbio
A process-bigraph wrapper for simbio that represents chemical reaction networks using Antimony or reaction specifications, rebuilds Antimony through libantimony and libSBML, and integrates the resulting ODEs with simbio's LSODA solver. Species concentrations are exposed through shared stores and emitted as additive per-step deltas.
viva-munk
A composable framework for simulating populations of growing, dividing cells with realistic 2D physics and shared chemical environments. Cells are capsule-shaped rigid bodies or multi-segment compound bodies that grow, divide, secrete particles, attach to surfaces, and interact physically through collisions and confinement; concentration fields use finite-difference diffusion and are coupled to cells through exchange steps.
Spatio-Flux
Spatio-Flux composes independently developed processes including metabolism, spatial transport, particle dynamics, and structural rewrites into executable simulations through typed interfaces and shared orchestration.
mbmm
A general implementation of the Mechanistic Bayesian Mixture Model framework that embeds an application-specific ordinary differential equation trajectory model inside a Bayesian mixture likelihood evaluated against Approximate Bayesian Computation reference banks, with covariate-linked logistic or multinomial gates.
Vivarium-chemotaxis
A Vivarium model integrating receptor activity, flagellar motility, gene expression, transport, metabolism, membrane potential, growth, and division for Escherichia coli chemotaxis.
viva-tumor-tcell
A multiscale agent-based model of the tumor microenvironment with tumor cells, T cells, dendritic cells, diffusing IFNg and tumor-debris fields, and cell-cell neighbor exchange.
Vivarium-chemotaxis
The repository implements Vivarium processes and composites for Escherichia coli chemotaxis, including chemoreceptor activity, flagella activity, proton motive force, and integrated metabolism, transport, transcription, translation, complexation, degradation, and division processes.