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viva-tumor-tcell
A multiscale agent-based tumor microenvironment model with tumor, T-cell, and dendritic-cell processes, diffusing IFNg and tumor-debris fields, cell-cell neighbor exchange, and phenotype conversion/exhaustion dynamics.
viva-tumor-Vivarium-2
A process-bigraph port of the multiscale agent-based tumor microenvironment model, including tumor, T-cell, and dendritic-cell biology, diffusing IFNg and tumor-debris fields, and cell-cell neighbor exchange.
Malinzi2018 - Enhancement of chemotherapy using oncolytic virotherapy
IA spatio-temporal mathematical model, in the form of a moving boundary problem, to explain cancer dormancy. Analysis covers temporal and spatio-temporal cases, stability, travelling waves, minimum invasion wave speeds, and numerical simulations of immune-induced tumour dormancy.
Tumor/T cell Microenvironment ABM
The model represents tumor cells, T cells, and related processes in a spatial microenvironment, including intracellular and intercellular interactions, soluble factors, cell movement, molecular fields, proliferation, phenotype changes, and cytotoxic killing. It is implemented on the Vivarium framework and can be initialized with multiplexed imaging datasets.
viva-tumor-tcell
A multiscale agent-based model of the tumor microenvironment with tumor cells, T cells, dendritic cells, diffusing IFNg and tumor-debris fields, and cell-cell neighbor exchange.